Cistanche Tubulosa Extract Empowers Skincare Innovation

Inthe global skincare market dominated by pure beauty and efficient active ingredients, Cistanche Tubulosa Extract is gaining increasing attention from international brands for its exceptional multifunctional skincare properties. This natural botanical ingredient, with its rich active compounds and robust scientific foundation, has emerged as a next-generation skincare raw material aligned with the demands of the European and American markets.

Research indicates that Cistanche extract is rich in phenethyl glycosides (such as echinacoside and astragaloside IV), cycloaromatic terpenoids, and polysaccharides. It delivers potent moisturizing, antioxidant, and restorative benefits, effectively enhancing skin barrier function and delaying signs of aging. This makes it an efficient natural solution for serums, creams, and masks.

Currently, this ingredient is widely incorporated into anti-aging, soothing repair, and premium moisturizing product lines. Its natural and sustainable properties align perfectly with the global market's demand for pure, potent, and eco-friendly ingredients.

As a leading supplier of plant-based active ingredients, Green Spring Technology employs advanced extraction and purification processes to produce high-purity, highly stable Cistanche tubulosa extracts. Strict adherence to international standards ensures clear ingredient profiles and consistent efficacy across every batch. We offer customized raw material solutions to empower brands in developing more competitive and market-differentiated skincare products, swiftly responding to the global clean beauty trend.

1. Cistanche Tubulosa Extract: Scientific Analysis of Active Components and Quality Control System for Precise Product Development

Cistanche Tubulosa extract, renowned for its rich active components and well-defined efficacy, has emerged as a high-value natural ingredient in pharmaceuticals, health foods, and personal care. Its core value stems from systematic component research and rigorous quality control.

1.1 Analysis of Primary Active Components

Cistanche tubulosa extract primarily contains two major categories of active ingredients:

· · · · ·· · · · · · · ·· · · · · · · · · · · ·· · · · · · · ·· · · · · · · ·· · · ·· · · ·· · · ·· · · · · · · ·· · · ·· · · ·· · · ·· · · ·· · · ·· · · ·· · · ·· · · ·· · · ·· · · ·· · · ·· · · ·Phenethyl glycosides: Represented by echinacoside and acteoside, these are the extract's signature functional components, present at significantly higher concentrations than in other Cistanche species;

· Polysaccharides: Composed of various monosaccharides such as fructose, galactose, and arabinose linked by diverse glycosidic bonds, featuring both linear and branched structures. These polysaccharides exhibit excellent compatibility and application stability.

1.2 Modern Analytical Methods Ensure Controllable Components and Consistent Quality

Advancements in analytical technology now enable precise qualitative and quantitative analysis of active components in Cistanche tubulosa extract:

· High-Performance Liquid Chromatography (HPLC/UPLC) Technology: Widely applied for separating and quantifying phenethyl glycosides like echinacoside and cistanoside, enabling scientific monitoring of component variations across harvest seasons and origins;

· Spectroscopic Coupling Techniques: Methods like HPLC-ESI-MS and Fourier Transform Infrared Spectroscopy (FTIR) enable rapid component identification and establishment of raw material fingerprinting, ensuring batch-to-batch consistency;

· Polysaccharide Characterization: Techniques including Multi-Angle Laser Light Scattering (MALLS) and Ion Chromatography determine polysaccharide molecular weight distribution and monosaccharide composition, providing comprehensive structural evaluation of raw materials;

· Mineral Element Analysis: Determines multiple mineral contents via ICP-AES and other methods, providing safety and nutritional data support for product development.

These systematic analytical methods provide a robust data foundation and scientific basis for raw material screening, seasonal harvesting, authenticity evaluation, and final product quality control of Cistanche tubulosa extract.

1.3 Green Spring Technology: Empowering Customer Product Innovation Through Scientific Quality Control

Leveraging modern analytical techniques and a rigorous quality control system, Green Spring Technology ensures every batch of Cistanche tubulosa extract meets the following standards:

· Clear Composition: Stable and well-defined levels of core active ingredients;

· Reliable Quality: Comprehensive control from raw materials to finished products, meeting relevant standards;

· Application Support: Providing complete component analysis reports and compliance documentation to facilitate rapid, compliant product launches.

Green Spring Technology is committed to delivering high-standard, traceable Cistanche tubulosa extract, collaborating to advance the innovative application of natural ingredients in the health industry.

2 Cistanche tubulosa Extract: Modern Technology Empowers High-Potency Natural Ingredients

Cistanche tubulosa extract, rich in active components like phenylethanol glycosides and polysaccharides, has become a vital ingredient in pharmaceuticals, health foods, and cosmetics. The precision and scientific rigor of its extraction process directly determine the final product's component content, active compound retention, and application efficacy.

2.1 Core Extraction Process and Technical Advantages

Modern extraction techniques significantly enhance the quality and yield of Cistanche tubulosa extract:

· Resin Purification Technology: Utilizing macroporous adsorption resins such as AB-8 enables efficient separation and enrichment of phenethyl glycosides. Through systematic optimization of sample pH, concentration, flow rate, and elution conditions, high-purity extraction is achieved.

· Dynamic extraction optimization: Based on single-factor and orthogonal experiments, reflux extraction with 40% ethanol was established as the core process. Research indicates extraction frequency is the key factor influencing yield, with optimization significantly enhancing active component extraction efficiency.

· Green innovative process: Integrated technologies like combined enzymatic hydrolysis and ultrasonic extraction are applied for polysaccharide extraction. This environmentally friendly, easy-to-operate process maximizes component activity retention while improving yield.

· Precision Process Control: Real-time monitoring of five or more phenethyl glycoside contents using HPLC and other techniques. Response surface methodology optimizes parameters including solvent ratios, solid-liquid ratios, temperature, and time throughout the process, ensuring process stability and batch consistency of extracts.

2.2 Green Spring Technology: Process Innovation and Quality Assurance

Leveraging these advanced processes, Green Spring Technology has established a rigorous scientific production system for Cistanche tubulosa extract:

· Precision Purification: Employing resin chromatography and other techniques to effectively enrich target components like echinacoside and astragaloside IV, ensuring controllable purity and stable content.

· Green Extraction: Actively integrating environmentally friendly technologies such as enzymatic methods and ultrasonic-assisted extraction to reduce organic solvent usage and enhance production sustainability.

· Comprehensive Quality Control: Integrating online detection with process optimization ensures compliance with stringent quality standards throughout all stages from raw materials to finished products.

Green Spring Technology is committed to delivering high-potency, high-purity, and consistently stable Cistanche tubulosa extracts through continuous process innovation, providing premium raw material solutions for pharmaceuticals, functional foods, cosmetics, and other sectors.

3 Cistanche tubulosa Extract: Multi-Mechanism Synergy for Skin Health and Radiance

Skin health maintenance is a complex system involving the interaction between intrinsic physiological processes and external environmental factors. Both natural internal processes and external conditions influence skin appearance. With its rich natural active ingredients, Cistanche tubulosa extract offers a scientifically grounded raw material solution for maintaining skin health and enhancing its visual texture through multi-targeted, multi-pathway mechanisms.

3.1 Core Active Ingredients and Skin Health

Cistanche tubulosa extract is rich in multiple natural active components, primarily including:

· Phenethyl alcohol glycosides (e.g., echinacoside, astragaloside IV)

· Polysaccharides (CDPS)

·D-mannitol, etc.

Research indicates these components synergistically support skin health through multiple mechanisms. For instance, appropriate additions of D-mannitol or Cistanche polysaccharides help increase skin hydroxyproline levels while supporting collagen fiber quantity and skin elasticity.

3.2 Mechanism of Action and Application Potential

In vitro studies demonstrate Cistanche tubulosa extract's positive impact on maintaining skin matrix structure.Experiments indicate that after treatment with appropriate extract doses, beneficial changes occur in the expression levels of certain biomarkers associated with collagen metabolism and moisture retention.

Research also reveals that Cistanche deserticola polysaccharides protect skin cells exposed to UVB irradiation by helping to inhibit oxygen radical chain reactions and supporting the self-repair capacity of skin tissue. Additionally, this ingredient has been reported to promote proliferation in various cell types.

Notably, phenethyl glycosides in Cistanche tubulosa exhibit UV-absorbing properties that mitigate skin damage from ultraviolet radiation. These compounds also enhance superoxide dismutase (SOD) activity, thereby exerting antioxidant effects.

Regarding skin tone regulation, research indicates that total phenethyl alcohol glycosides from Cistanche tubulosa modulate tyrosinase activity. Experiments demonstrate that appropriate concentrations of these glycosides inhibit UVB-induced changes in tyrosinase activity and regulate mRNA transcription levels of related genes, offering a novel solution for brightening skin tone and evening out complexion.

Green Spring Technology: Premium Raw Material Supplier

Green Spring Technology employs advanced extraction processes to produce high-purity, high-potency Cistanche tubulosa extracts, ensuring:

· Stable and controllable active ingredient content

· Excellent batch-to-batch quality consistency

· Strong compatibility with cosmetic formulations

· Comprehensive technical documentation

Our extracts are widely applicable in:

· Anti-aging skincare products

· Antioxidant personal care items

· Skin repair formulations

· Skin-brightening cosmetics

Green Spring Technology is committed to providing clients with premium, stable, and compliant Cistanche tubulosa extracts, jointly advancing the innovative application of natural ingredients in cosmetics.

4 perspectives

As consumer demands for cosmetic efficacy and safety continue to rise, Cistanche tubulosa extract is gaining prominence as a functional ingredient in skincare due to its rich active components and well-defined mechanisms of action. Current research provides robust scientific evidence supporting its applications in antioxidant protection, photoprotection, skin repair, and complexion regulation.

Moving forward, we look forward to collaborating with industry partners to advance human clinical trials and data accumulation for this ingredient, further validating its efficacy in real-world usage scenarios. Together, we will drive innovation and application of Cistanche tubulosa extract in cosmetics.

Green Spring Technology remains committed to empowering products through science, dedicated to providing customers with high-purity, high-standard, and high-performance Cistanche tubulosa extract alongside professional application support. We assist brands in developing more competitive skincare solutions.

Contact us at helen@greenspringbio.com or WhatsApp: +86 13649243917 for a sample to test.

Références:

[1] Hao Shanshan, Chen Sumai, Yan Donghai, et al. Progrès de la recherche sur l’application de Cistanche deserticola dans les cosmétiques [J]. Science of Daily Chemical Industry, 2021, 44(9): 36-41.

[2] Commission nationale de la pharmacopée. Pharmacopée du peuple ' S république de Chine édition 2010 I [M]. Beijing: China Pharmaceutical Science and Technology Press, 2010: 12.

[3] LI Wenlan, BAI Jing, ZANG Baoshan, et al. HPLC-ESI-Q-TOFMS/MS analyse des composants de Cistanche deserticola Y.C. Ma. Entrer dans le sang du site actif des pseudo-œstrogènes [J]. Journal of Mass Spectrometry, 2015, 36(3): 1.

[4] HUGS, HURYJ, JIAJM, et al. Effet du traitement à l’acide 2-aminoindan-2- phosphonique sur l’accumulation de salidroside et de quatre Glycosides phéyléthanoïdes dans la culture cellulaire en suspension de Cistanche deserticola. [J]. Plant Cell Reports, 2011, 30(4): 665-674.

[6] Zhou Ye, Li Wei, Han Lifeng, et al. Identification de Cistanche par les méthodes HPLC-ESI-MS et FTIR d’origines différentes [J]. Spectroscopy and Spectral Analysis, 2015, 35(4): 1056-1061.

[7] Qian Hao, Yu Fangjun, Geng Zongcheng, et al. Etude Comparative de la teneur en quatre glycosides phényléthanoïdes chez Cistanche deserticola récoltés au cours de différentes saisons [J]. Journal of Pharmaceutical Analysis, 2016, 36(11): 1971.

[8] Wang Xueyuan, Xiao Bo, Zhang Zhifeng et al. Détermination de la teneur en échinacoside, acteoside, galactitol, bétaïne et polysaccharide soluble dans Cistanche deserticola récolté à différents moments et recherche sur son authenticité [J]. Chinese Herbal Medicine, 2017, 48(18): 3841-3844.

[9] Qin Wenting, Su Meifeng, Luo Xiaomei, et al. Analyse Qualitative des glycosides phényléthanoïdes et des polysaccharides chez Cistanche deserticola d’origines différentes [J]. Journal de l’université de médecine traditionnelle chinoise du Liaoning, 2018(7): 77-81.

[10] Zhu Nailiang, Xu Rong, Wu Haifeng, et al. Étude Comparative sur les empreintes digitales de Cistanche deserticola et Cistanche tubulosa [J]. Chinese Journal of Pharmacy, 2016, 51(13): 1116-1119.

[11] Nan Zedong, Ren Huazhong, Zhao Mingbo et al. Identification de 17 composants dans des cultures Cistanche deserticola Y.C. Ma par HPLC-MS [J]. Chinese Journal of Experimental Traditional Medicine, 2018, 24(20): 62-67.