Poudre de diosgénine

Qu’est-ce que la diosgénine?

La diosgénine, communément connue sous le nom de diosgénine, est une sorte de diosgénine stéroïde naturellement synthétisée par des plantes et existe largement dans les tubercules des plantes légumineuses et des Dioscoreaceae. C’est une matière première importante pour la synthèse des médicaments d’hormone stéroïde. Il a de nombreux effets pharmacologiques remarquables, tels que anti-tumoral, anti-inflammatoire, antioxydant, et a une valeur médicinale élevée.

Green Spring fournit de la poudre de diosgénine extraite de tubercules d’igname sauvages. C’est une DHEA naturelle (déhydroepiandrosterone), qui peut favoriser le métabolisme des cellules épidermiques de la peau, améliorer la fonction hydratante de la peau, et également aider à améliorer le corps.

Spécification: 

Règlement:

Il est conforme à la réglementation de l’ue.

Benefits:

Antitumor Activity

In vivo and in vitro studies have shown that diosgenin has cytotoxicity to a variety of tumor cells, including breast cancer cells, colon cancer cells, prostate cancer cells, lung cancer cells, gastric cancer cells, Osteosarcoma cells, etc. It can play an anti-tumor role by inhibiting tumor cell proliferation, inducing tumor cell apoptosis, blocking cell cycle, and anti-tumor metastasis.

Hepatoprotective Effect

Diosgenin powder can effectively inhibit the cell viability of HSC-T6, LX-2, and primary rat hepatic stellate cells (HSCs), while liver cells are not affected. Diosgenin also has a good protective effect on alcoholic liver injury, which is achieved by reducing oxidative stress, the production of inflammatory cytokines, cell apoptosis, and liver steatosis.

Hypoglycemic Effect

The combination of NPH insulin and diosgenin in the treatment of elderly type 2 diabetes is more effective in reducing blood sugar with good safety, which may be related to the reduction of Glycated hemoglobin formation.

Anti Osteoporosis Effect

Dioscin can promote the proliferation of osteoblasts and inhibit the formation of Osteoclast. Research has shown that after diosgenin treatment of MC3T3-E1 cells, ER- α、 ER- β、 Lrp5 β- The expression of both catenin and Bcl-2 proteins increased, and the ratio of OPG/RANKL increased, depending on the LRP5 pathway, thereby promoting osteoblast proliferation.

Applications:

Pharmaceutical Intermediate:

Diosgenin powder is an important steroidal saponin and an important raw material for Semisynthesis steroidal compounds.