Sophora Japonica extrait Kaempferol

Qu’est-ce que Sophora Japonica extrait Kaempferol?

Sophora Japonica extract kaempferol est l’ingrédient actif kaempferol extrait du fruit de Sophora Japonica. C’est une poudre cristalline jaune, légèrement soluble dans l’eau, soluble dans l’éthanol chaud, l’éther DMSO, et d’autres solvants organiques. Le kaempférol possède de fortes propriétés antioxydantes, qui peuvent récupérer l’excès de radicaux superoxydés du corps et prévenir les dommages oxydatifs à l’adn et aux cellules. Il est principalement utilisé comme anticancéreux, inhibiteur de fertilité, antiépileptique, anti-inflammatoire, antioxydant et anti-ulcère.

vert printemps Technology fournit l’extrait de Kaempferol de Sophora Japonica de haute pureté, qui a une pureté allant jusqu’à 98% et est disponible en nanoparticules, nanoparticules liposomales et d’autres formes. Le kaempférol de nanoparticule résout le problème qu’il est difficile de dissoudre dans l’eau, il a une solubilité, une stabilité, une émulsification et des propriétés antioxydantes plus fortes, et a été employé comme matière première pharmaceutique.

Fondée en 2000, Green Spring Technology est une société de biotechnologie leader en Chine, qui se consacre à la recherche et au développement d’extraits de plantes de haute qualité. Il a obtenu de nombreuses certifications telles que Halal, casher, COSMOS, BRC, IFS, FDA, ISO9001, ISO22000 et ainsi de suite. Elle dispose d’un système de gestion de la qualité interne systématique et organise sa production en stricte conformité avec les normes de qualité ISO, HACCP et autres. Les produits sont conformes aux normes ue EC396, ue 2023/915 et aux normes les plus élevées en matière de résidus de solvants.

Spécification: 

Règlement:

Il est conforme à la réglementation de l’ue.

Benefits:

Antibacterial and Anti-Inflammatory

Studies have shown that kaempferol has good antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). The K-Br paper slide method shows that a concentration of 50 mg/tablet can make the circle of inhibition of MRSA up to 8.5 mm, and its antibacterial activity against Vibrio cholerae and Enterococcus faecalis is also very good. In antiviral, kaempferol showed concentration-dependent inhibition at non-cytotoxic concentrations. In anti-inflammation, kaempferol mainly inhibits the expression of inflammatory factors to achieve anti-inflammatory effects.

Contributes to Anticancer

Kaempferol was applied to human gastric cancer cells MGC-803 (in vitro assay), and DAPI staining was observed under a fluorescence microscope, and the results showed that the chromatin of the nucleus was condensed, and the nucleus was dissolved and irregularly shaped. According to the results of the MIT method, it was found that kaempferol could inhibit the proliferation of cancer cells. According to the comet electrophoresis method, most of the cancer cells showed a comet tail shape, which resulted in cellular DNA damage, and finally concluded that kaempferol could inhibit the proliferation of human gastric cancer cells.

Beneficial for Diabetes

Researchers established a mouse model to verify the hypoglycemic and hypolipidemic effects of kaempferol in diabetic mice. Serum triglyceride, total cholesterol, blood glucose, malondialdehyde, glutathione peroxidase, and superoxide dismutase activities were measured in diabetic mice fed with kaempferol and diabetic mice fed with thirst-quenching pills in a control test.

The results showed that kaempferol could effectively reduce serum triglyceride, total cholesterol, blood glucose, and malondialdehyde levels in mice, and significantly increase the activities of serum glutathione peroxidase and superoxide dismutase, with 10 mg/(kg-bw-d) as the optimal dose. Kaempferol can delay the development of diabetes mellitus. The above studies have demonstrated the therapeutic effect of kaempferol on diabetes mellitus.

May Beneficial for Hepatoprotection

In a mouse model of acute liver failure with kaempferol, kaempferol improved hepatic function and pathological changes in mice and inhibited endoplasmic reticulum stress-induced apoptosis in human hepatocyte cell line 7702 cells. It may protect hepatocytes by inhibiting endoplasmic reticulum stress through inhibiting the expression of the endoplasmic reticulum stress-specific apoptotic protein CHOP, which suggests that the use of kaempferol may provide a new intervention for acute liver injury.

Applications:

In Pharmaceutical:

Sophora extract kaempferol is a widely used natural compound with various biological activities such as antioxidant and anti-inflammatory. Due to its unique physicochemical properties, Kaempferol is widely used in various fields. In the field of medicine, kaempferol is mainly used in the treatment of cardiovascular and neurological diseases. In addition, it is used in the preparation of some anticancer drugs and antiparasitic drugs.