10% poudre d’icariine

Qu’est-ce que la poudre d’icariin?

L’extrait d’epimedium est un produit traité à partir des tiges et des feuilles séchées d’epimediumbrevicornum et d’autres espèces d’epimedium. Les principaux ingrédients actifs sont les flavonoïdes, y compris le glycoside d’epimedium, l’hypoglycoside d’epimedium, le glycoside C d’epimedium grandiflorum, et le glycoside A d’epimedium asiaticum, B, C, et ainsi de suite. Il a un effet androgène semblable et est utilisé pour améliorer l’immunité du corps et abaisser la pression artérielle. Il a un effet inhibiteur évident sur l’infection causée par Staphylococcus aureus et le poliovirus. Il a également pour effet de supprimer la toux, l’expectorant et l’asthme. L’extrait d’epimedium est principalement utilisé comme matière première pour les produits de santé pour améliorer la fonction sexuelle.

À propos de Icariin est l’un des principaux ingrédients actifs de l’extrait d’epimedium, qui est 8-isopentenyl flavonoïde glycosides. Le Glycoside d’epimedium peut augmenter le flux sanguin cardiovasculaire, favoriser la fonction hématopoïétique, la fonction immunitaire, et le métabolisme osseux, eta également pour effet de tonifier le rein et aphrodisiaque, anti-vieillissement, et ainsi de suite.

La poudre d’icariine fournie par la technologie Green Spring est une poudre brun à jaune clair qui est faite à partir des herbes locales à Longnan, Province de Gansu et est produite par plus de 20 procédures, telles que le prétraitement des herbes, le broyage, l’extraction, la concentration, l’adsorption, l’élution, le séchage par pulvérisation, le broyage et le tamisage. Le processus de fabrication entier adopte tout l’équipement de production d’acier inoxydable et l’équipement à haute efficacité de détection de phase liquide pour l’essai. Le produit a passé le test d’identification et les métaux lourds, les résidus de solvants, les microorganismes et les hap sont conformes aux normes d’exportation.

Spécification:

Règlements:

Il est conforme à la réglementation de l’ue.

Benefits:

Sexual Function Enhancement

Icariin is considered to be an effective sexual function enhancer, which can stimulate sexual desire, increase libido, improve erectile function, and is effective in men with erectile dysfunction (ED). Icariin can inhibit ferrous sulfate/hydrogen peroxide-induced oxidative stress damage in human spermatozoa, activate the ERK1 /2 signaling pathway, promote the proliferation of trophoblast Sertoli's in the testis, and enhance the male reproductive function; it can regulate the hypothalamic-pituitary-gonadal axis, up-regulate the expression of dopamine and 5-hydroxytryptophan in the hypothalamus, and activate the PI3K/AKT /eNOS /NO signaling pathway to increase NO, serum testosterone concentration, shorten capture latency and ejaculation latency, increase capture and ejaculation rates as well as testicular and prostate indices, and improve the sexual function of male mice; it can activate NO-cyclic guanosine monophosphate signaling pathway, inhibit the expression of phosphodiesterase type 5, and improve erectile dysfunction.

Beneficial for Neurological Disorders     

Icariin is beneficial in a variety of neurological disorders such as cerebral ischaemia, Alzheimer's disease, Parkinson's disease, multiple sclerosis, and depression. Icariin can increase the level of superoxide dismutase (SOD). Decrease the expression of amyloid precursor protein and β-secretase, and reduce the production and accumulation of Aβ. It can also reduce Aβ-mediated atrophy of axons and dendrites, and improve the spatial learning and memory ability of Alzheimer's disease model rats. Icariin can also inhibit Aβ-induced hyperphosphorylation of serine 396, 404, and threonine 205 of tau protein. Thus, it can play the role of protecting nerve cells.

Protecting the Skeletal System

Icariin can promote the formation and activation of osteoblasts and inhibit the formation and function of osteoclasts to alleviate osteoporosis. Icariin can activate ERα-Wnt/β-catenin and Notch signaling pathway, and up-regulate the expression of runt-related transcription factor 2, a key gene in osteoblasts, to play the role of osteogenesis. It can activate the mitogen-activated protein kinase (MAPK) signaling pathway and increase the gene expression of type I collagen, osteocalcin, and osteopontin. Enhance the self-renewal capacity of bone mesenchymal stem cells (BMSCs) in vivo and in vitro. Induces the differentiation of BMSCs to osteoblasts, which in turn enhances osteogenic differentiation. In addition, Icariin can promote estrogen synthesis and has estrogen-like effects. It can activate extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK), and promote the proliferation of osteoblasts. Activates BMP-2/Smad4 to increase osteoblast viability.

Protection of the Cardiovascular System  

Icariin can block angiotensin II-induced cardiomyocyte hypertrophy and apoptosis by inhibiting the activation of JNK and p38 pathways. It activates ERK, removes reactive oxygen species, and inhibits oxidative stress in cardiomyocytes. Icariin also activates the PI3K/Akt/endothelial nitric oxide synthase (eNOS) signaling pathway and reduces creatine kinase. Ischemic modification of albumin and lactate dehydrogenase levels reduced apoptotic cells, myocardial infarction area, and ameliorated myocardial ischemia-reperfusion injury in rats. Down-regulates matrix metalloproteinase 2 and 9 activities, improves cardiomyocyte apoptosis and attenuates left ventricular dysfunction and cardiac remodeling.

Regulating the Immune System

Icariin can improve the condition of autoimmune diseases such as rheumatoid arthritis, bronchial asthma, multiple sclerosis, and systemic lupus erythematosus, which is related to its regulation of lymphocyte function. Icariin can inhibit the differentiation of helper T cells (Th) 1 and 17, and improve autoimmune encephalomyelitis in mice. Icariin can inhibit the activation of STAT3 in T cells and down-regulate the proportion of Th17 cells. It can inhibit the production of interleukin-17 and improve the symptoms of rheumatoid arthritis. It can regulate the ratio of Th1/Th2 cells in lung tissues of asthmatic rats and the balance of Th17/regulatory T cells in asthmatic mice, and improve asthma. It can increase the activity of lymphokine-activated killer cells as well as natural killer cells to improve human immunity.

Applications:

For Feed Product:

Test results show that adding Epimedium Extract to the feed promotes the development of the thymus, spleen, and bursa, improves the effect of vaccines for Newcastle Disease and Avian Influenza, strengthens immunity, improves resistance to infectious diseases, and reduces the mortality rate as well as the morbidity rate. Epimedium Extract Icariin has anti-respiratory syndrome. It has been verified by tests that adding Epimedium Extract to feed can prevent and control epidemic diarrhoea in pigs. Rapidly regulate the intestinal physiological function of female animals and optimize the intestinal environment. Improve the reproductive ability of sows and promote the growth of animals.

For Health Product:

Epimedium extract has the effect of enhancing gonadal function, regulating body's immune function, promoting bone growth, delaying aging, and so on. Epimedoside powder is used as a raw material in health products.