Poudre d’apigénine 98%

Qu’est-ce que la poudre d’apigénine 98%?

L’apigénéine est un flavonoïde que l’on trouve largement dans une variété de plantes telles que le persil, le céleri, l’oignon, la camomille, le thym, l’origan, le basilic, le thé, la bière, le vin, le pamplemousse et l’orange. Il a une colonne vertébrale flavonoïde caractéristique à 15 atomes de carbone contenant des structures d’anneaux multiples, des groupes de cétone et des groupes hydroxyle multiples, qui confèrent à l’apigénine des propriétés électroniques riches et des affinités de liaison diverses.

Des études menées dans le pays et à l’étranger ont montré que l’apigénine avait une variété d’activités biologiques telles que antitumorale, antioxydante, anti-inflammatoire et hypoglycémique, etc. En tant que substance active naturelle avec un potentiel pour un large éventail d’applications, il a un grand potentiel de développement dans les domaines de l’alimentation, des nutraceutiques et des produits pharmaceutiques.

La poudre d’apigénine est une poudre fine jaune clair extraite du céleri ou de la camomille par la méthode du CO2 supercritique. La température d’extraction supercritique de CO2 est basse (environ 35℃), qui peut efficacement protéger les composants thermosensibles de l’apigénine de la destruction. L’ensemble du processus ne nécessite pas de solvants organiques et ne produit pas de substances nocives pour le corps humain et l’environnement. Efficacité élevée d’extraction, consommation basse d’énergie, processus sûr et stable d’extraction, et non-toxique, incolore, et insipide.

La technologie Green Spring fournit la poudre d’apigène 98%, extraite des fleurs de camomille, avec une grande pureté, des propriétés stables et une faible teneur en humidité, et peut être stockée pendant une plus longue période. Il est conforme aux normes ue EC396, ue 2023/915 et aux normes les plus élevées en matière de résidus de solvants.

Green Spring Technology est une société leader de technologie d’extrait d’usine en Chine avec 24 ans d’expérience dans les extraits d’usine. Il dispose de 7 certifications et 7 brevets. Elle a mis en place un système de traçabilité parfait pour tous ses produits. Green Spring a obtenu des certifications Halal, casher, COSMOS, BRC, IFS, FDA, ISO et bien d’autres. Des rapports de tests de tiers faisant autorité sont disponibles.

Spécification: 

Règlement:

Il est conforme à la réglementation de l’ue.

Benefits:

Helps with Sleep

Studies have shown that apigenin has a positive effect on sleep. In animal models, apigenin reduces motor activity and increases sedation, which may contribute to shorter sleep latency and improved sleep quality. Additionally, apigenin can promote sleep by reducing the stress response and increasing levels of BDNF (Brain Derived Neurotrophic Factor) and serotonin.

Anti-Aging

Apigenin exerts its anti-aging effects through a variety of mechanisms. In animal models, apigenin extends the lifespan of fruit flies and nematodes, and in mice, it improves learning memory, reduces tumour proliferation and prolongs survival. The anti-aging mechanisms of apigenin may include reduction of oxidative stress, modulation of immune responses, protection of neurovascular coupling, enhancement of mitochondrial function, and improvement of metabolic health.

Anti-tumour

Studies have shown that apigenin activates transcription factor 3 thereby inhibiting Id1 expression and reducing the proliferation and tumourigenesis of ovarian cancer A2780 cells. Epithelial mesenchymal transition (EMT) is a very important mechanism for initiating and promoting tumour metastasis. Apigenin was found to inhibit metastasis, invasion, and colony formation of non-small cell lung cancer cells with different states of epidermal growth factor receptor by suppressing Snail/Slug-mediated epithelial mesenchymal transition.

Lowering Blood Sugar

Studies have shown that apigenin repairs cellular damage induced by streptozotocin (STZ) in pancreatic β-cells, prevents lipid peroxidation and protein carbonylation, reduces cellular DNA damage, and significantly reduces reactive oxygen species (ROS) production in rat insulinoma cell lines. Apigenin and naringenin effectively restored high glucose-reduced Bcl-2 expression and Akt phosphorylation and protected endothelial cells from damage by inhibiting phosphorylated expression of protein kinase CβII (PKCβII) and downstream reactive oxygen species (ROS) production in high glucose-exposed endothelial cells. In conclusion, apigenin and naringenin may ameliorate endothelial dysfunction by modulating ROS/caspase-3 and NO pathways.

Antioxidant

Numerous scientific studies have revealed the good antioxidant activity of apigenin. One study found the ameliorative effect of apigenin as a natural antioxidant on MTX (methotrexate) hepatotoxicity. Liver antioxidant indexes were significantly elevated in the apigenin pretreatment group, whereas serum AST, ALT, and ALP levels were markedly reduced, and hepatic MDA (Malondialdehyde), TNF-α (Tumour Necrosis Factor α), NO, and IL-1β (Interleukin 1β) levels were significantly reduced. In addition, the hepatoprotective effect of apigenin was confirmed by histological evaluation of the liver, and apigenin could prevent MTX-induced hepatotoxicity by reducing oxidative stress and inflammation.

Vasodilator

After removing the vascular endothelium, it was found that apigenin still had a vasodilatory effect but it was weakened, suggesting that its target point of action included vascular endothelial cells in addition to vascular smooth muscle cells. Preliminary mechanistic studies showed that the vasoconstrictive effect of apigenin against phenylephrine was not only related to the impediment of Ca2+ influx through the modulation of Ca2+ channels but also to the release of NO and the increase in cGMP levels. cGMP levels.

Applications:

In Cosmetics:

Apigenin's absorption of ultraviolet rays is concentrated in the B region (wavelength between 280~320nm), which is strong absorption and can be used in sunscreen series cosmetics. In the A area (wavelength between 320~400nm) the absorption is small, so the low concentration of apigenin can be used as a skin tanning agent to join the use of tanning oil. Apigenin powder can be used in creams; it can be compounded with vitamin B1, vitamin B6, vitamin B12, vitamin C, etc.; it can also be compounded with essential oils such as chamomile oil, calendula oil, and almond oil. High concentrations of apigenin can inhibit melanin cell activity, can be added to sunscreen, cream, essence, lotion, mask, and other cosmetics; and can be used in shampoo, and conditioner.

Apigenin has a strong absorption capacity for UVB ultraviolet rays can protect against radiation damage, and can be used in sunscreen cosmetics. Apigenin has strong antioxidant properties and a strong capturing ability for various oxygen-containing free radicals, which can prevent oxidative degradation of oils and fats. Apigenin also has anti-inflammatory activity, preventing skin problems such as blister evidence, keratosis pilaris, and hyperkeratosis. In addition, apigenin relieves itchy scalp and can be used in hair care products. Therefore, apigenin powder is increasingly used in various kinds of efficacious cosmetics.