Vitamine naturelle K2 MK7 poudre 1,5%

Qu’est-ce que la poudre naturelle de vitamine K2 MK7?

La vitamine K2, également connue sous le nom de MK-7 (Menaquinone-7), est un dérivé liposoluble de la vitamine K. C’est l’une des formes les plus actives de la famille de la vitamine K et a des fonctions physiologiques importantes. Le 1er juillet 2017, le comité de pharmacopée des États-Unis a conclu que la vitamine K2MK-7 présentait une biodisponibilité supérieure. MK-7 est une vitamine K2 (méthylnaphthoquinone) de 7 unités d’isoprénoïde formant une chaîne de côté avec la formule moléculaire C46H64O2 et le poids moléculaire de 649. 00.

La vitamine K2 MK7 a une biodisponibilité plus élevée, une demi-vie plus longue et une activité anti-ostéoporotique plus importante que la MK-4. La vitamine MK7 est la meilleure forme de vitamine K2 et le natto est la meilleure source de vitamine K2 MK7. Il est important de noter que seul le "trans" La configuration du MK7 est biologiquement active.

La vitamine K2 MK7 favorise la carboxylation de la protéine extrahépatique dépendant de la vitamine K2 (VK2DP), de l’ostéocalcine (OC) et de la protéine matrix Gla (MGP), qui est capable de lutter contre l’ostéoporose.

Le 31 mars 2020, la revue Nutrients a publié une revue des effets de la vitamine K2 MK7 sur la masse osseuse et la force osseuse par Toshiro Sato et d’autres. Conclusion: comparée à la vitamine K2 MK4, la vitamine K2 MK7 a une biodisponibilité plus élevée et une demi-vie plus longue, et est plus susceptible d’augmenter la densité osseuse et d’améliorer la qualité osseuse, la force osseuse, et la production de collagène.

Green Spring Technology fournit de la vitamine naturelle K2 MK7 poudre 1,5%, qui est produite par une souche pure de Nattokinella, grâce à la biotechnologie moderne induite production de souches hautement actives de vitamine K2 MK7, avec une meilleure bioactivité et une biodisponibilité élevée. Pas d’extraction par solvant organique, séparation physique et technologie de concentration, pas de pollution secondaire, pas de conservateurs, pas d’additifs, pas de solvants chimiques, pas de synthèse, activité stable et durable.

Spécification:

Règlements:

Il est conforme à la réglementation de l’ue.

Benefits:

Anti-Osteoporosis

Vitamin K2 MK7 powder promotes bone formation and reduces bone resorption by activating osteocalcin, stimulating osteoblast differentiation, regulating extracellular matrix mineralization, and inhibiting osteoclastogenesis, thereby preventing osteoporosis. Moreover, animal studies and clinical trials over the years have proved that Vitamin K2 MK7 has the health benefits of promoting bone health and preventing osteoporosis. Therefore, MK7 supplements have been approved for marketing in China, and experts recommend that clinicians use supplements containing Vitamin K2 MK7 powder to prevent and treat osteoporosis.

Improving Dental Health

One of the major regulatory proteins for dental health is osteocalcin, a protein essential for bone metabolism that can be activated by vitamin K2. Dentin is the calcified tissue underneath the enamel on teeth, and osteocalcin triggers a mechanism that stimulates the growth of new dentin.

Helps Fight Cancer

Vitamin K2 MK7 can inhibit tumour growth by negatively regulating tyrosine kinase and phosphodiesterase activities associated with cell carcinogenesis, as well as modulating regulatory factors associated with cell proliferation, ultimately leading to cell cycle inhibition in tumour cells.

Improve Diabetes

Vitamin K2 MK7 powder upregulates the insulin gene, promotes pancreatic beta cells, and releases insulin, which can improve the body's metabolic levels and help diabetics recover.

Promote Calcium Absorption

Vitamin K2 contributes to bone development or bone density by carboxylating glutamic acid residues in osteocalcin to gamma-carboxyglutamic acid residues, which activates osteocalcin to form "calcium claws" that bind to hydroxyapatite and promote bone mineral salt deposition. The researchers conducted a double-blind controlled trial of vitamin K2 MK7 powder supplementation for 8 weeks in 55 children and adolescents, measuring serum levels of uncarboxylated osteocalcin (ucOC), carboxylated osteocalcin (cOC), and MK7 for calcium absorption.

The results show that moderate supplementation of Vitamin K2 MK7 powder in healthy adolescent children can increase the concentration of MK7 and increase osteocalcin carboxylation; ucOC is secreted by osteoblasts, and vitamin K2 converts ucOC to cOC, which further forms a calcium claw that leads calcium into the bone and promotes calcium absorption.

Inhibits Vascular Calcification

Vitamin K2 reduces the risk of cardiovascular problems by activating Matrix Gla Protein (MGP), which inhibits the calcification of calcium ions in the arteries.

Researchers in Rotterdam, the Netherlands, conducted a 10-year study involving more than 4,800 people (≥55 years of age) to investigate whether dietary intake of vitamin K2 was associated with cardiovascular problems such as aortic calcification. The results showed that vitamin K2 intake led to a reduction in the relative risk of cardiovascular problems and that subjects who consumed more than 32.7 μg of vitamin K2 per day had a 50 percent reduction in the risk of aortic calcification compared to those who consumed lower doses.

Applications:

For Health Products:

In the international nutraceutical market, Vitamin K2 powder products include Vitamin K2 (MK-4) and Vitamin K2 MK7 powder, of which:Vitamin K2 MK4 is synthetic and has a short half-life, while Vitamin K2 MK 7 powder is mostly produced by fermentation and has a longer period of action. Natural Vitamin K2 MK7 Powder has been widely used as a nutraceutical additive.